Eczema as a skin disease revealed susceptibility to psychological factors causing the emergence of various psychoanalytic studies. In this study, the skin-ego structure and early childhood relations of two cases are investigated by Projective Tests. The skin-ego theory developed by Didier Anzieu was used. During the first years of life the skin is an interface between mother and infant. Accordingly, the first stimuli transferred by the mother and traces of the ego might be projected on the body surface. Starting from this point, maternal functions for a skin disease will be questioned. During a pre-interview one case reported that tactile needs were not satisfied. It was observed that the skin-ego structure of the cases were damaged or related to that period difficulties of representation were experienced. In the early childhood relation with the mother persecution phantasies and intense emotions were found. Archaic anxieties induced disconnected representations and the use of primitive defenses. This information could be used throughout therapeutic practices.