Beyond being a symptom, hyperactivity in daily life can be considered as a populer metaphor that contains within itself a certain amount of cute mischievousness. It is almost a key to the doors of a psychiatry clinic. As a syptom hyperactivity is demonstrated through a state of not being able to stop or calm down. This state seems to carry signs from the first years of infancy. The baby uses all its extremities towards both inner and outer stimuli. It contracts it muscles and this pysical activity is usually followed by a sudden scream or cry. The mother or the care giver is expected to get this message coming from the baby. Hence the baby relaxes and this extreme act that aims to be message ends. Different than in adults, depression can be observed as a form of irritability in children. The usage of manic defense mechanisms and acting outs are common against depressive emotinal states. Even if today?s popular psychological disorder hyperactivity appears as being totally the opposite of depression, when investigated in depth, it can turno ut to be hand in hand with it. It is possible for symptoms of hyperactivity to be seen as defences against depression. The emptiness inside is wished to be ignored by constant movements and the usage of the bodyly mechanisms. Since the feeling of emptiness on a consciouss level brings with it a type of pain that cannot easily be processed psychologically, this confession is banned through this constant moving. Attention Deficit Hyperactivity Disorder as a sydrome is a common diagnose. It would be risky to diagnose almost every child that is brought to the clinic as hyperactive without searching and understanding the unique meanings of these types of behaviors. This article aims to discuss the meanings of symptoms that often appear in school children such as attention deficit, hyperactivity, the state of not being able to be motivated, boredom and their possible relation to depression thorough a psychological, clinical and neuro-biological perspective.